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Advanced Phenotype Search (Combinatorial Query Builder):
Phenotype
=
contains
exists
does not exist
begins with
ends with
!=
>
>=
<
<=
COUNT =
COUNT !=
COUNT >
COUNT >=
COUNT <
COUNT <=
AB aster resembles P1 aster
AB nuclear migration abnormal
AB or P1 spindle orientation aberrant
AB spindle orientation abnormal
ABa, ABp and EMS divide synchronously
Aberrant AB or P1 spindle orientation
Aberrant Cytoplasmic Structures
Aberrant cell-cell contacts at the four-cell stage
Aberrant nuclear reassembly
Abnormal blebbing
Abnormal coloration
Abnormal one-cell shape
Abnormal pronuclei
Abnormal size of pronucleus
Abs
Adl
Age
Altered cell-cell contacts
Altered timing of second division
Altered timing of second division (synchrony)
Areas devoid of yolk granules
Asymmetry of Division abnormal
Bli
Bmd
Catastrophic one-cell arrest
Ced
Centrosome Attachment abnormal
Chromosome Segregation (karyomeres) abnormal
Clr
Complex Phenotype
Con
Cortical Dynamics abnormal
Cpa
Cyk
Cytokinesis defect
Cytokinesis problems
Daf
Defect
Delayed P0 spindle rotation
Delayed P1 division
Delayed at pronuclear contact
Developmental Delay
Division axis of ABa or ABp aberrant
Dpy
Dramatic cytoplasmic blebbing
EMS divides after and is smaller than P2
EMS divides before and is smaller than P1
EMS extends too far anteriorly
EMS fails to extend anteriorly
Ectopic cleavage furrows
Ectopic furrows
Egg Size abnormal
Egg production ceases in injected animal
Egg shape/size abnormal
Egl
Emb
Embryos arrest at different stages
Entry Into Interphase abnormal
Esp
Etv
Evl
Exaggerated asynchrony
Exaggerated pseudocleavage
Excessive blebbing
Failure to form pronucleus
Fem
Fgc
Fog
Four-cell stage configuration abnormal
Four-cell stage nuclei: size/shape abnormal
Four-cell stage: cross-eyed
General Pace of Development abnormal
Glp
Gom
Gon
Granular cytoplasm
Gro
Growth defect
Him
Hya
Inadequate test
Indistinct maternal pronucleus
Integrity of Membranous Organelles defective
Lag
Large cytoplasmic granules
Larval Arrest-Early (L1/L2)
Larval Arrest-Late (L3/L4)
Larval Lethal-Early (L1/L2)
Larval Lethal-Late (L3/L4)
Led
Let
Lethal
Lin
Lon
Loose mitotic furrow
Loose spindle
Lpd
Lva
Lvl
Mab
Mec
Mei
Meiotic arrest
Mel
Mig
Mlt
Mog
Morphology defect
Movement defect
Mul
Multiple cavities
Multiple maternal pronuclei
Multiple nuclei
Multiple nuclei in 1, 2, or 4-cell embryos
Multiple paternal pronuclei or aberrant centrosomes
Multiple vacuoles
Mut
Muv
Nmo
No developing embryos seen 48 hours after dsRNA injection
Npo
Nuclear Appearance abnormal
Nuclei reform next to cell division remnant
Number/age of embryos atypical
Ocs
Oma
Ooc
Osmotic Integrity defective
Osmotic sensitivity
Osmotically/ pressure sensitive
Oth
Other
Overall pace of events slow
P0 cortical ruffling abnormal
P0 cytokinesis: completion/stability abnormal
P0 cytokinesis: furrow ingression abnormal
P0 cytokinesis: furrow specification abnormal
P0 cytoplasmic flows reduced/absent
P0 pronuclear centration absent
P0 pronuclear envelope breakdown delayed
P0 pronuclear meeting position abnormal
P0 pronuclear migration reduced/absent (female)
P0 pronuclear migration reduced/absent (male)
P0 pronuclear rotation
P0 pronuclei: number abnormal
P0 pronuclei: size/shape abnormal
P0 pseudo-cleavage furrow abnormal
P0 spindle absent
P0 spindle assembly: bipolarity abnormal
P0 spindle does not rotate
P0 spindle elongation abnormal
P0 spindle integrity abnormal
P0 spindle poles abnormal
P0 spindle positioning defect
P0 spindle positioning problems
P0 spindle positioning problems (posterior)
P0 spindle positioning: asymmetry abnormal
P0 spindle rocking abnormal
P1 aster abnormal
P1 nuclear migration/rotation absent/reduced
P1/AB asynchrony of divisions abnormal
P1/AB cortical activity exaggerated
P1/AB cytokinesis abnormal
P1/AB nuclear separation: cross-eyed
P1/AB nuclei: number abnormal
P1/AB nuclei: size/shape abnormal
P1/AB spindle assembly abnormal
P2 and EMS divide synchronously
Pace of P-Lineage abnormal
Passage Through Meiosis defective
Pat
Patchy
Paternal pronucleus migrates
Pch
Pleiotropic
Pna
Pnm
Polar bodies abnormal
Polar body reabsorbed
Prl
Prm
Pro
Pronuclear breakdown asynchronous
Pronuclear migration defects
Pronuclear/Nuclear Appearance abnormal
Pronuclei can meet centrally
Pronuclei fail to migrate
Pronuclei meet more centrally
Prz
Pseudocleavage absent
Pseudocleavage problems
Pvl
Pvu
Rde
Reduced fecundity of injected worm
Reproductive defect
Reversed asynchrony
Rol
Rot
Rup
Sck
Severe Pleiotropic Defects
Sister Chromatid Separation abnormal (Cross-eyed)
Sle
Slow cell cycle
Slu
Sma
Small embryos
Spd
Spi
Spindle Assembly abnormal
Spindle Elongation/Integrity abnormal
Spindle positioning problems
Spn
Spo
Ste
Sterile F0/Fertility Problems
Sterile F1
Sterility/Impaired Fertility in F0
Stp
Stress Resistance
Synchronous second division
Tetrapolar spindle
Tum
Unc
Unclassified
Unclear: multinucleate
Unfertilized oocytes laid
Var
Vul
WT
WT_postembryonic_morphology
Yolk granules: density reduced
Yolk granules: size abnormal
aldicarb_resistant
embryonic defect
mult
no escapers
post-embryonic defect
END
AND
OR
XOR
AND NOT
OR NOT
XOR NOT
Phenotype
=
contains
exists
does not exist
begins with
ends with
!=
>
>=
<
<=
COUNT =
COUNT !=
COUNT >
COUNT >=
COUNT <
COUNT <=
AB aster resembles P1 aster
AB nuclear migration abnormal
AB or P1 spindle orientation aberrant
AB spindle orientation abnormal
ABa, ABp and EMS divide synchronously
Aberrant AB or P1 spindle orientation
Aberrant Cytoplasmic Structures
Aberrant cell-cell contacts at the four-cell stage
Aberrant nuclear reassembly
Abnormal blebbing
Abnormal coloration
Abnormal one-cell shape
Abnormal pronuclei
Abnormal size of pronucleus
Abs
Adl
Age
Altered cell-cell contacts
Altered timing of second division
Altered timing of second division (synchrony)
Areas devoid of yolk granules
Asymmetry of Division abnormal
Bli
Bmd
Catastrophic one-cell arrest
Ced
Centrosome Attachment abnormal
Chromosome Segregation (karyomeres) abnormal
Clr
Complex Phenotype
Con
Cortical Dynamics abnormal
Cpa
Cyk
Cytokinesis defect
Cytokinesis problems
Daf
Defect
Delayed P0 spindle rotation
Delayed P1 division
Delayed at pronuclear contact
Developmental Delay
Division axis of ABa or ABp aberrant
Dpy
Dramatic cytoplasmic blebbing
EMS divides after and is smaller than P2
EMS divides before and is smaller than P1
EMS extends too far anteriorly
EMS fails to extend anteriorly
Ectopic cleavage furrows
Ectopic furrows
Egg Size abnormal
Egg production ceases in injected animal
Egg shape/size abnormal
Egl
Emb
Embryos arrest at different stages
Entry Into Interphase abnormal
Esp
Etv
Evl
Exaggerated asynchrony
Exaggerated pseudocleavage
Excessive blebbing
Failure to form pronucleus
Fem
Fgc
Fog
Four-cell stage configuration abnormal
Four-cell stage nuclei: size/shape abnormal
Four-cell stage: cross-eyed
General Pace of Development abnormal
Glp
Gom
Gon
Granular cytoplasm
Gro
Growth defect
Him
Hya
Inadequate test
Indistinct maternal pronucleus
Integrity of Membranous Organelles defective
Lag
Large cytoplasmic granules
Larval Arrest-Early (L1/L2)
Larval Arrest-Late (L3/L4)
Larval Lethal-Early (L1/L2)
Larval Lethal-Late (L3/L4)
Led
Let
Lethal
Lin
Lon
Loose mitotic furrow
Loose spindle
Lpd
Lva
Lvl
Mab
Mec
Mei
Meiotic arrest
Mel
Mig
Mlt
Mog
Morphology defect
Movement defect
Mul
Multiple cavities
Multiple maternal pronuclei
Multiple nuclei
Multiple nuclei in 1, 2, or 4-cell embryos
Multiple paternal pronuclei or aberrant centrosomes
Multiple vacuoles
Mut
Muv
Nmo
No developing embryos seen 48 hours after dsRNA injection
Npo
Nuclear Appearance abnormal
Nuclei reform next to cell division remnant
Number/age of embryos atypical
Ocs
Oma
Ooc
Osmotic Integrity defective
Osmotic sensitivity
Osmotically/ pressure sensitive
Oth
Other
Overall pace of events slow
P0 cortical ruffling abnormal
P0 cytokinesis: completion/stability abnormal
P0 cytokinesis: furrow ingression abnormal
P0 cytokinesis: furrow specification abnormal
P0 cytoplasmic flows reduced/absent
P0 pronuclear centration absent
P0 pronuclear envelope breakdown delayed
P0 pronuclear meeting position abnormal
P0 pronuclear migration reduced/absent (female)
P0 pronuclear migration reduced/absent (male)
P0 pronuclear rotation
P0 pronuclei: number abnormal
P0 pronuclei: size/shape abnormal
P0 pseudo-cleavage furrow abnormal
P0 spindle absent
P0 spindle assembly: bipolarity abnormal
P0 spindle does not rotate
P0 spindle elongation abnormal
P0 spindle integrity abnormal
P0 spindle poles abnormal
P0 spindle positioning defect
P0 spindle positioning problems
P0 spindle positioning problems (posterior)
P0 spindle positioning: asymmetry abnormal
P0 spindle rocking abnormal
P1 aster abnormal
P1 nuclear migration/rotation absent/reduced
P1/AB asynchrony of divisions abnormal
P1/AB cortical activity exaggerated
P1/AB cytokinesis abnormal
P1/AB nuclear separation: cross-eyed
P1/AB nuclei: number abnormal
P1/AB nuclei: size/shape abnormal
P1/AB spindle assembly abnormal
P2 and EMS divide synchronously
Pace of P-Lineage abnormal
Passage Through Meiosis defective
Pat
Patchy
Paternal pronucleus migrates
Pch
Pleiotropic
Pna
Pnm
Polar bodies abnormal
Polar body reabsorbed
Prl
Prm
Pro
Pronuclear breakdown asynchronous
Pronuclear migration defects
Pronuclear/Nuclear Appearance abnormal
Pronuclei can meet centrally
Pronuclei fail to migrate
Pronuclei meet more centrally
Prz
Pseudocleavage absent
Pseudocleavage problems
Pvl
Pvu
Rde
Reduced fecundity of injected worm
Reproductive defect
Reversed asynchrony
Rol
Rot
Rup
Sck
Severe Pleiotropic Defects
Sister Chromatid Separation abnormal (Cross-eyed)
Sle
Slow cell cycle
Slu
Sma
Small embryos
Spd
Spi
Spindle Assembly abnormal
Spindle Elongation/Integrity abnormal
Spindle positioning problems
Spn
Spo
Ste
Sterile F0/Fertility Problems
Sterile F1
Sterility/Impaired Fertility in F0
Stp
Stress Resistance
Synchronous second division
Tetrapolar spindle
Tum
Unc
Unclassified
Unclear: multinucleate
Unfertilized oocytes laid
Var
Vul
WT
WT_postembryonic_morphology
Yolk granules: density reduced
Yolk granules: size abnormal
aldicarb_resistant
embryonic defect
mult
no escapers
post-embryonic defect
END
AND
OR
XOR
AND NOT
OR NOT
XOR NOT
Phenotype
=
contains
exists
does not exist
begins with
ends with
!=
>
>=
<
<=
COUNT =
COUNT !=
COUNT >
COUNT >=
COUNT <
COUNT <=
AB aster resembles P1 aster
AB nuclear migration abnormal
AB or P1 spindle orientation aberrant
AB spindle orientation abnormal
ABa, ABp and EMS divide synchronously
Aberrant AB or P1 spindle orientation
Aberrant Cytoplasmic Structures
Aberrant cell-cell contacts at the four-cell stage
Aberrant nuclear reassembly
Abnormal blebbing
Abnormal coloration
Abnormal one-cell shape
Abnormal pronuclei
Abnormal size of pronucleus
Abs
Adl
Age
Altered cell-cell contacts
Altered timing of second division
Altered timing of second division (synchrony)
Areas devoid of yolk granules
Asymmetry of Division abnormal
Bli
Bmd
Catastrophic one-cell arrest
Ced
Centrosome Attachment abnormal
Chromosome Segregation (karyomeres) abnormal
Clr
Complex Phenotype
Con
Cortical Dynamics abnormal
Cpa
Cyk
Cytokinesis defect
Cytokinesis problems
Daf
Defect
Delayed P0 spindle rotation
Delayed P1 division
Delayed at pronuclear contact
Developmental Delay
Division axis of ABa or ABp aberrant
Dpy
Dramatic cytoplasmic blebbing
EMS divides after and is smaller than P2
EMS divides before and is smaller than P1
EMS extends too far anteriorly
EMS fails to extend anteriorly
Ectopic cleavage furrows
Ectopic furrows
Egg Size abnormal
Egg production ceases in injected animal
Egg shape/size abnormal
Egl
Emb
Embryos arrest at different stages
Entry Into Interphase abnormal
Esp
Etv
Evl
Exaggerated asynchrony
Exaggerated pseudocleavage
Excessive blebbing
Failure to form pronucleus
Fem
Fgc
Fog
Four-cell stage configuration abnormal
Four-cell stage nuclei: size/shape abnormal
Four-cell stage: cross-eyed
General Pace of Development abnormal
Glp
Gom
Gon
Granular cytoplasm
Gro
Growth defect
Him
Hya
Inadequate test
Indistinct maternal pronucleus
Integrity of Membranous Organelles defective
Lag
Large cytoplasmic granules
Larval Arrest-Early (L1/L2)
Larval Arrest-Late (L3/L4)
Larval Lethal-Early (L1/L2)
Larval Lethal-Late (L3/L4)
Led
Let
Lethal
Lin
Lon
Loose mitotic furrow
Loose spindle
Lpd
Lva
Lvl
Mab
Mec
Mei
Meiotic arrest
Mel
Mig
Mlt
Mog
Morphology defect
Movement defect
Mul
Multiple cavities
Multiple maternal pronuclei
Multiple nuclei
Multiple nuclei in 1, 2, or 4-cell embryos
Multiple paternal pronuclei or aberrant centrosomes
Multiple vacuoles
Mut
Muv
Nmo
No developing embryos seen 48 hours after dsRNA injection
Npo
Nuclear Appearance abnormal
Nuclei reform next to cell division remnant
Number/age of embryos atypical
Ocs
Oma
Ooc
Osmotic Integrity defective
Osmotic sensitivity
Osmotically/ pressure sensitive
Oth
Other
Overall pace of events slow
P0 cortical ruffling abnormal
P0 cytokinesis: completion/stability abnormal
P0 cytokinesis: furrow ingression abnormal
P0 cytokinesis: furrow specification abnormal
P0 cytoplasmic flows reduced/absent
P0 pronuclear centration absent
P0 pronuclear envelope breakdown delayed
P0 pronuclear meeting position abnormal
P0 pronuclear migration reduced/absent (female)
P0 pronuclear migration reduced/absent (male)
P0 pronuclear rotation
P0 pronuclei: number abnormal
P0 pronuclei: size/shape abnormal
P0 pseudo-cleavage furrow abnormal
P0 spindle absent
P0 spindle assembly: bipolarity abnormal
P0 spindle does not rotate
P0 spindle elongation abnormal
P0 spindle integrity abnormal
P0 spindle poles abnormal
P0 spindle positioning defect
P0 spindle positioning problems
P0 spindle positioning problems (posterior)
P0 spindle positioning: asymmetry abnormal
P0 spindle rocking abnormal
P1 aster abnormal
P1 nuclear migration/rotation absent/reduced
P1/AB asynchrony of divisions abnormal
P1/AB cortical activity exaggerated
P1/AB cytokinesis abnormal
P1/AB nuclear separation: cross-eyed
P1/AB nuclei: number abnormal
P1/AB nuclei: size/shape abnormal
P1/AB spindle assembly abnormal
P2 and EMS divide synchronously
Pace of P-Lineage abnormal
Passage Through Meiosis defective
Pat
Patchy
Paternal pronucleus migrates
Pch
Pleiotropic
Pna
Pnm
Polar bodies abnormal
Polar body reabsorbed
Prl
Prm
Pro
Pronuclear breakdown asynchronous
Pronuclear migration defects
Pronuclear/Nuclear Appearance abnormal
Pronuclei can meet centrally
Pronuclei fail to migrate
Pronuclei meet more centrally
Prz
Pseudocleavage absent
Pseudocleavage problems
Pvl
Pvu
Rde
Reduced fecundity of injected worm
Reproductive defect
Reversed asynchrony
Rol
Rot
Rup
Sck
Severe Pleiotropic Defects
Sister Chromatid Separation abnormal (Cross-eyed)
Sle
Slow cell cycle
Slu
Sma
Small embryos
Spd
Spi
Spindle Assembly abnormal
Spindle Elongation/Integrity abnormal
Spindle positioning problems
Spn
Spo
Ste
Sterile F0/Fertility Problems
Sterile F1
Sterility/Impaired Fertility in F0
Stp
Stress Resistance
Synchronous second division
Tetrapolar spindle
Tum
Unc
Unclassified
Unclear: multinucleate
Unfertilized oocytes laid
Var
Vul
WT
WT_postembryonic_morphology
Yolk granules: density reduced
Yolk granules: size abnormal
aldicarb_resistant
embryonic defect
mult
no escapers
post-embryonic defect
END
AND
OR
XOR
AND NOT
OR NOT
XOR NOT
1
2
3
4
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![Adult](JavaScript:void window.open("/cgi-bin/popUpImage.cgi?imgName=N2wormfinal.png","RNAiDB Help","toolbar=no, location=no, directories=no, status=no, menubar=no, scrollbars=yes, resizable=no, copyhistory=no, width=1000, height=550"))
